So testosterone might be thought of as the hormone thatembodies the essence of what is manly, but it is nothing withoutits mate LH. LH is an important part of the equation. In someinstances LH has successfully treated low libido, erectile dysfunctionand infertility (Crenshaw 1997). But it only works whenadministered in its natural pulsatile fashion. All these patterns arequintessential. In 2000, Daniel Keenan and Johannes Veldhuisfrom the University of Virginia with Weimin Sun from thePathoGenesis Corporation in Seattle focused on understandingthe mathematical pattern behind the GnRH–LH–testosteroneor the brain–ball set-up. It came down to this:

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